Biobanking Security: Proactive Strategies for Preventing Biospecimen Loss
Although critical to biomedical research and drug development, biospecimen safety and integrity are often overlooked and under-recognized issues. Lack of attention to specimen storage, handling, transport, and tracking can quickly compromise reproducibility, waste irreplaceable samples, and delay clinical progress. In this panel, experts from GenVault discuss proactive strategies for safeguarding valuable biological materials that work […]
Practical Strategies to Enhance the Quality and Potency of mRNA Constructs
In this GEN Biotechnology webinar, Vicky Smith, PhD, an expert in RNA biology, will provide a practical blueprint for enhancing mRNA quality using proven manufacturing strategies from TriLink’s 25+ years of expertise. She will review a range of strategies to optimize critical parameters such as UTR tuning, codon optimization, cap choices, in vitro transcription (IVT) […]
Emerging Aspiration Technologies in Ureteroscopy: Enhancing Stone Clearance and Safety
Challenges in traditional ureteroscopy, including poor visibility, stone migration, incomplete stone clearance, and elevated intrarenal pressures, have resulted in a paradigm shift in treatment options for a disease that affects nearly 10% of people worldwide. Specifically, numerous devices have now been developed that focus on aspiration, with expected benefits of enhanced stone clearance and safety. […]
Target, Track, Treat: Optimizing GI Cancer Management with Molecular Residual Disease Testing
Gastrointestinal (GI) cancer remains one of the deadliest forms of cancer worldwide, with the American Cancer Society predicting about 30,000 new cases and more than 10,000 deaths in the U.S. in 2025. GI cancer relapses remain a major challenge due to small fragments of cancer that persist in the body after a patient has completed […]
Tiny Traces, Big Impact: Changing the Paradigm in Breast Cancer Management with MRD Testing
In breast cancer care, a recurring clinical dilemma is identifying patients who have residual disease and are at risk of relapse. The ability to detect minimal residual disease (MRD) at the molecular level is emerging as a critical tool for optimizing patient care and outcomes. Growing evidence supports the use of circulating tumor DNA (ctDNA) […]
Tails of Innovation: Enhancing RNA Therapeutics via Novel Poly(A) Modifications
As the potential of mRNA-based medicines expands, researchers are making exciting strides in overcoming the challenges associated with the intrinsic instability and immunostimulatory properties of exogenous mRNA. By introducing various modifications through chemical or enzymatic methods across the entire mRNA sequence—from cap to tail—translational activity can be enhanced, and immunogenicity risks reduced. To that end, […]