Multimedia Content from Sage

Diagnostic Relevance of microRNAs: Understanding Gene Regulation in Thyroid Cancer

MicroRNAs are powerful therapeutic and diagnostic tools that shape cellular behavior through coordinated signaling pathways. These small, non-coding RNAs regulate gene expression by influencing the translation of mRNA to protein, offering a powerful regulatory approach for treating diseases, with increasing interest in oncology applications such as thyroid cancer. In this roundtable webinar, a panel of […]

Go from Target ID to IND Faster with Validated TBD Tools

Facial Nerve Repair: Practical Use of Nerve Connectors, Protectors, and Allografts

The practice of nerve repair continues to evolve alongside advances in science, surgical technique, and clinical care. Although resources supporting the use of nerve connectors, protectors, and processed allografts in peripheral nerve repair are expanding, literature guiding head and neck reanimation remains limited. Surgeons must optimize outcomes in facial nerve repair while balancing cost, efficiency, […]

Advancing Hemodialysis Access Care with AV Grafts: Surgical Excellence and Long-Term Graft Performance

Reliable vascular access remains the cornerstone of hemodialysis, yet each patient’s journey through chronic kidney disease is unique. The 2019 Kidney Disease Outcomes Quality Initiative (KDOQI) vascular access guidelines update introduced a patient‑focused strategy that tailors vascular access choices to individual circumstances and personal goals.   As AV graft utilization continues to play a key […]

Biobanking Security: Proactive Strategies for Preventing Biospecimen Loss

Although critical to biomedical research and drug development, biospecimen safety and integrity are often overlooked and under-recognized issues. Lack of attention to specimen storage, handling, transport, and tracking can quickly compromise reproducibility, waste irreplaceable samples, and delay clinical progress. In this panel, experts from GenVault discuss proactive strategies for safeguarding valuable biological materials that work […]

Practical Strategies to Enhance the Quality and Potency of mRNA Constructs

In this GEN Biotechnology webinar, Vicky Smith, PhD, an expert in RNA biology, will provide a practical blueprint for enhancing mRNA quality using proven manufacturing strategies from TriLink’s 25+ years of expertise. She will review a range of strategies to optimize critical parameters such as UTR tuning, codon optimization, cap choices, in vitro transcription (IVT) […]

Emerging Aspiration Technologies in Ureteroscopy: Enhancing Stone Clearance and Safety

Challenges in traditional ureteroscopy, including poor visibility, stone migration, incomplete stone clearance, and elevated intrarenal pressures, have resulted in a paradigm shift in treatment options for a disease that affects nearly 10% of people worldwide. Specifically, numerous devices have now been developed that focus on aspiration, with expected benefits of enhanced stone clearance and safety. […]

Precision Under Pressure: New Frontiers in Flexible Ureteroscopy

Target, Track, Treat: Optimizing GI Cancer Management with Molecular Residual Disease Testing

Gastrointestinal (GI) cancer remains one of the deadliest forms of cancer worldwide, with the American Cancer Society predicting about 30,000 new cases and more than 10,000 deaths in the U.S. in 2025. GI cancer relapses remain a major challenge due to small fragments of cancer that persist in the body after a patient has completed […]

Tiny Traces, Big Impact: Changing the Paradigm in Breast Cancer Management with MRD Testing

In breast cancer care, a recurring clinical dilemma is identifying patients who have residual disease and are at risk of relapse. The ability to detect minimal residual disease (MRD) at the molecular level is emerging as a critical tool for optimizing patient care and outcomes. Growing evidence supports the use of circulating tumor DNA (ctDNA) […]